49ers Bounce Back: Injuries and Comebacks in Focus

San Francisco, California, USATue Nov 11 2025
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The San Francisco 49ers are facing a crucial phase of their season. After a tough loss to the Los Angeles Rams, the team is looking to regroup and focus on their upcoming game against the Arizona Cardinals. One of the biggest challenges for the 49ers has been injuries. Coach Kyle Shanahan has been cautious about the team's health, especially with key players like Nick Bosa, Fred Warner, and Mykel Williams still out. However, there is some good news on the injury front. Quarterback Brock Purdy, who has been dealing with a turf toe injury, is getting closer to returning to practice and potentially starting in the next game. Wide receiver Ricky Pearsall Jr. , who has missed the last six games due to a knee injury, may also return to practice. Defensive tackle Alfred Collins, who has been dealing with a hip injury, is also expected to practice and be available for the game against the Cardinals. Shanahan has been cautious about declaring players ready to return, emphasizing the need for consistent practice and positive feedback from the players themselves. Until Purdy can practice consecutively without any limitations, Mac Jones will continue to start. Jones has been performing well, with a passer rating of 115. 7, which is better than Purdy's best rating this season. The 49ers' margin for error is slim, and every game is crucial. Shanahan has emphasized the need for the team to play well over the next seven weeks to secure their place in the playoffs. The team's performance against the Rams was not up to par, but Shanahan believes that the team can bounce back and play better in the upcoming games. In addition to the injury updates, there have been some notable developments on the field. The 49ers had two too-many-men on the field penalties, which Shanahan attributed to communication issues. The defensive performance was also a concern, with the Rams scoring 42 points. Shanahan acknowledged that the defense needs to improve, especially in covering against blitzes. On the offensive line, Ben Bartch and Spencer Burford have been providing depth and performing well against a strong Rams front. The 49ers also had cornerback Assante Samuel Jr. in for a tryout, but Shanahan did not have a chance to meet with him. Samuel has had a solid career but has been dealing with injuries. Looking ahead, the 49ers will need to focus on their upcoming game against the Cardinals. The team's performance will be crucial in determining their playoff chances. With key players returning and the team's resilience, the 49ers have the potential to make a strong comeback and secure their place in the playoffs.