HEALTH

ESI: A Fresh Tool for Tracking Emphysema Severity

Pisa, Central ItalyWed Sep 23 2026

Researchers in Pisa, Italy gathered data from 685 adults between 2009 and 2011. This group had an average age of 53.3 years and mostly were men. They used standard questionnaires along with spirometry tests. The main goal was to see how well a new measurement called ESI works for studying breathing problems.

The ESI calculation uses three key numbers: peak expiratory flow, forced vital capacity, and forced expiratory flows at 25%, 50%, and 75% of FVC. The score runs from zero for no emphysema to ten for very severe cases. In this group, the average ESI was 1.16 with some variation. Half of participants scored around 0.98 when looking at the middle range.

Men, former smokers, older folks, and people with asthma or COPD tend to have higher scores. Those who struggled with daily tasks, visited doctors often, or needed hospital care for breathing issues also scored higher. Every step up in the ESI range meant a bigger chance of respiratory trouble, less ability to do everyday things, and more health service use. Even people without serious breathing problems showed similar patterns.

This new index could help spot early lung damage even before someone has obvious symptoms. That makes it useful for catching problems early and preventing them from getting worse. It gives public health researchers a better picture of how common emphysema really is across different groups.

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