Brain inflammation, a significant factor in neurodegenerative diseases, is managed by tiny immune cells called microglia. These cells can be pro-inflammatory (M1) or anti-inflammatory (M2). We know that human stem cells from umbilical cords (hUCMSCs) can release substances that reduce inflammation.
Triple-negative breast cancer (TNBC) is tough to tackle due to issues like poor blood vessels and high tumor cell load. These problems make it hard for CAR-T cells, a type of immune cell therapy, to work well. Researchers found that when there are fewer CAR-T cells compared to tumor cells, the immun
Imagine if detecting skin cancer could be as simple as snapping a picture. Scientists are working on just that! They're using a special kind of computer program called convolutional neural networks (CNNs), and these aren't your average programs. They're like super-smart detectives that can spot patt
Lots of people have both coronary artery disease and valvular heart disease. This means they often need two big surgeries: coronary artery bypass grafting and valve replacement or repair. After these procedures, doctors usually prescribe a mix of anticoagulants and antiplatelets to prevent blood clo
Have you ever heard about people who suddenly withdraw from their social lives for long periods? This condition is called Hikikomori. It's not just about being shy; it's a complex issue that affects people’s daily routines and their families. Some individuals with Hikikomori might seem fine, while o
Ever wondered how your weight might affect back pain treatment? A recent study looked into this, focusing on the impact of obesity on a common procedure called lumbar transforaminal epidural steroid injections (TFESIs). These injections are often used to relieve pain in the lower back. The research
Imagine mixing two different drugs to see what happens. Scientists did exactly that with Albuvirtide (ABT), a new HIV drug, and Rifampicin (RIF), an antibiotic. They gave these drugs to healthy volunteers and checked their blood using advanced lab tests. Turns out, taking RIF with ABT made ABT work
Imagine you've had a spinal cord injury. You're one of the many who now live with neuropathic pain (NP), a debilitating condition that often doesn't respond well to medications. But what if there was another way to combat this pain? Enter exoskeletons: these robotic suits could help people with spin
Did you know that orthopaedic surgery is one of the least diverse medical specialties? Most doctors in this field are White men. Recently, there's been a push to make the profession more inclusive. To see if these efforts are working, we need to understand the current demographics. Let's dive into t
Imagine you're in a doctor's office, and instead of waiting two hours for a blood test, you only need to wait one hour. Sounds simpler, right? That's the idea behind the 1-hour oral glucose tolerance test (OGTT). This test measures how well your body handles sugar after a drink packed with glucose.
