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Researchers tested a new way to treat cancer when doctors don't know where it started. Some patients got a drug chosen because of the unique genes in their tumor. Others received more rounds of standard chemotherapy. All of them had already completed three rounds of chemo and saw their cancer stop growing for a while. After more than a year of follow-up, the group with gene-matched treatment went longer without their cancer getting worse. On average, they lived about six months without disease progression, compared to just over four months for the chemo group. The risk of the disease worsening was roughly 25 percent lower for those who got the gene-guided approach. How long people survived also favored the gene-matched group. They lived on average fifteen months, while the other group li

The American College of Cardiology and the American Heart Association have released a new guide for doctors who treat first responders. It focuses on firefighters, police officers, and military personnel who face unique heart risks on the job. The guide helps clinicians decide if someone is fit for full duty. It also talks about how a heart event could affect teammates and the community. The statement is split into eleven parts. Each part is written by a team of experts in sports cardiology and tactical operations. For every section, the authors created easy‑to‑read tables that list key points. They also pulled together the latest research that specifically involves tactical athletes. The layout follows the same pattern as a similar guide for competitive athletes. The first section expla

Scientists have found a way to read the spin state of a single carbon atom inside a special silicon carbide crystal. They placed the crystal so its long axis lines up with a strong 3. 4‑tesla magnet. They used special pulse tricks and a version of silicon that lacks extra isotopes. The magnetic field was set to 3. 4 tesla, which is strong enough to keep the spins aligned for a long time. The technique gave them a clear signal about 35 percent strong, letting them see the carbon’s nuclear magnetic resonance lines. They saw that the electron spin of the defect talks to carbon atoms that sit far away, in the fifth or sixth layers around the defect. At a chilly 120 K, the carbon spins wiggle in a steady rhythm, and the rhythm lasts about ten milliseconds before fading. The whole process works

More than 828 million people around the world deal with type 2 diabetes every single day. That number is huge, and it keeps growing. The biggest culprits behind this health crisis are obesity and something called insulin resistance. When your body stops responding properly to insulin, sugar builds up in your blood instead of getting used for energy. Here is the interesting part. Diabetes does not just appear overnight. It develops slowly, often starting with a condition called prediabetes. This is basically a warning sign that your blood sugar is running higher than normal but has not hit diabetes levels yet. For people who are obese or insulin resistant, this stage becomes a crucial opportunity to step in and change direction. Scientists call it a clinically relevant window because it gi

Kids today can gamble on their phones anytime. Apps and online sites have taken gambling out of the old casino walls and put it right in a pocket. This easy access means young people see gambling as part of everyday life, not just a night out. Ads for betting show up during sports games, making the activity look fun and cool. The messages say gambling is exciting, stylish, and safe. When kids see that over and over, they start to think it’s normal. Family habits and friends also shape how youth view gambling. If a parent bets on a game, or if a friend talks about winning, it can push a teen toward trying it. At the same time, some peers may warn each other away, showing the mix of push and pull. Young people are not just passive. They suggest tighter rules on ads, more education, and gi

Doctors often need to know fast if a patient has a bacterial infection, especially in emergencies. Current tests can take too long or need fancy labs. Researchers built a simple test that can give a quick answer right at the bedside. The test uses CRISPR technology paired with a protein named dCas9 to find the exact DNA piece from the bacteria. When that piece is found, it helps tiny gold particles covered with a special molecule stick together. This sticking makes the solution shift from red to purple and creates spots that boost a Raman signal. So you can see the color change with your eye or get a more precise reading with a small Raman device. Because the method zeros in on the target DNA, it is very specific and can spot as few as ten bacterial cells in a milliliter of liquid. The w

Scientists often complain that real eye experiments are expensive and slow. They also face strict rules that make animal work hard to approve. Because of this, many labs are turning to tiny, artificial setups that can copy the eye’s protective layer. Building these tiny models is tricky. Getting blood vessels to grow inside a dish and making the tiny structures work together is a big hurdle. Researchers wanted a new way to study how nutrients and medicines move across the retinal barrier without using live animals. The team created a mini‑eye chamber that looks like the back of the eye. They placed a thin, spun‑out fiber sheet—made from PLGA or gelatin—between a fluid chamber and a tiny channel network. The channels were etched into a 15‑mm silicone disc using a laser. The design was copi

In the Amazon region of Ecuador, Indigenous groups dealing with leishmaniasis frequently rethink what they eat while trying to feel well again. A recent study looked at sixty-eight people from seven different Indigenous communities. It asked how and why people change their meals when they are fighting this disease. People in these communities see food and health as deeply connected. They think about more than just what they put on their plate. They also pay attention to how food is cooked and how people behave around it. Many believe that certain foods can change how the sickness moves through the body. This belief is not about cause and effect in a scientific way. It works more like a relationship, where food qualities echo body qualities. Researchers call this way of thinking analogical

A recent study questions whether formative latent variables can truly capture psychological concepts. Researchers revisited a 2005 paper that warned about bias in path estimates when formative models are treated as reflective ones. The new analysis used simulations to test the original claims. It found that the bias in unpaired path coefficients was not caused by model misspecification. Instead, scaling differences between variables explained the distortion. Once those differences were adjusted for, the bias nearly vanished. The study also challenged the need for formative indicators. These indicators were meant to define the latent variable. But the research showed they were redundant. The latent variables got their identity from reflective indicators used for model identification, not