Colorectal cancer (CRC) is a tough opponent, but scientists are finding new ways to fight it. They've discovered that some CRCs have mutations in ARID1A and TP53 genes. These mutations make the cancer cells more vulnerable to a type of treatment that targets WEE1. Here's how it works: ARID1A helps
In Brazil, the environment agency Ibama is cracking down on meatpacking companies, including JBS SA, for allegedly buying cattle from farms that have illegally cleared parts of the Amazon rainforest. Ibama has started looking into 12 meatpacking plants, saying they might have been involved in a sche
The Batista brothers, Joesley and Wesley, are behind JBS, the world's top meat producer. They've had a rough ride with the law, facing charges for bribing over 1, 800 politicians in Brazil. Despite this, they're set to list their company on the New York Stock Exchange. This move comes after a decade
Researchers have been exploring how to create DNA-based tools that can operate under extreme conditions. Most DNA tools are designed to work in environments similar to those found in living cells. The goal is to create tools that can function in unusual conditions. One recent effort f
Mitochondria are tiny powerhouses inside our cells. They generate energy for our bodies to function. There are cases where these powerhouses don't work right. This can lead to some serious health issues. One such issue is a group of diseases that affect how people move. These are called mitocho
Iron is a big deal for plants. It is crucial for many processes. These include breathing, making chlorophyll, and helping with photosynthesis. When plants don't get enough iron, their roots have to work harder. This is where a special enzyme comes in. It is called H+ -ATPase. This enzyme helps lower
Ever wondered how hagfish digest their food and their role in the evolution of vertebrates? These creatures have an unusual digestive process. Their gut fluid is acidified like that of many invertebrates. This process is carried out by a mechanism called the vesicular-type H+-ATPase, or VHA for sho
Ever thought about how tiny machines in our bodies make energy? Meet ATP synthase, a tiny motor inside cells. It has two main parts, F O and F 1 , and a central part called the γ-subunit that's just 1 nanometer long. This subunit twists while making energy, like a little propeller. Each twist o
Malaria has a sneaky way of spreading from humans to mosquitoes, thanks to tiny structures called gametocytes. These act like mysterious switchboards, turning on and off when needed. So, what's the secret to their quick transformation? A team of researchers decided to zoom in on the mitochondria, th
Carlos Alcaraz, the 21-year-old Spanish tennis sensation, is in Turin for the ATP Finals. He's won big this season, but now he's fighting a familiar foe: his health. Alcaraz started his campaign with a loss to Casper Ruud, but he bounced back with a win over Alexander Rublev. During his matches, he'
