Hey there! Let’s talk about delirium and frailty in older adults. You know how sometimes older folks get confused and disoriented - that’s delirium. And frailty? Well, it’s like when your grandma or grandpa just seems to be losing their get-up-and-go. But here’s the interesting part: these two often
For years, pathologists have been using CD34 immunohistochemistry (IHC) to study bone marrow (BM) biopsies and clot sections. The QBEND10 primary antibody clone is widely favored, but other aspects of the testing process vary greatly across different labs and in published research. To address this i
Did you know that women struggling with infertility often have trouble sleeping? Research is showing that there's a big connection between sleep problems and fertility issues in women. This is a complicated topic, and scientists are trying to figure out why sleep is so important for reproductive hea
You might think that everyone would be excited to join a study that promises to help them live healthier lives. But when it comes to behavioral clinical trials focused on lifestyle changes, men seem to be less interested than women. A recent study, let's call it the ELM trial, looked into why men mi
Imagine having an operation and waking up with less pain and needing fewer strong painkillers. That's what VVZ-149, a new type of pain-blocking drug, aims to do. This small molecule targets two key components in our pain system – the glycine transporter type 2 and the serotonin receptor 5-HT2A. Re
Let's talk about a powerful duo in the fight against advanced kidney cancer. Nivolumab and ipilimumab, often called NIVO + IPI, are like the dynamic duo of immunotherapy. They're used to treat people with intermediate- or high-risk advanced or metastatic renal cell carcinoma (mRCC). Now, you might b
In the United States, many patients with polycythemia vera (PV), a blood disorder, are treated in community practices. Recent research looked at 5871 PV patients to understand their blood counts, treatments, and outcomes after six months of taking hydroxyurea (HU), a common drug used to lower blood
You’ve probably heard that shockwave therapy can help with Achilles tendon pain. But does it really work? Let's dig into a study that tried to find out. Researchers wanted to know if adding shockwave therapy to exercise could help people with insertional Achilles tendinopathy feel better and move ea
Imagine a life changed by a small device. Nick Fournie, now 62, knows this well. His depression journey started 40 years ago, turning his life upside down. Medications caused more harm than good. Then, a nurse suggested vagus nerve stimulation (VNS). This treatment uses electric pulses to stimulate
You might think all doctors are the same, but that's not true. Some are better than others, and this can affect how well patients get better. Usually, researchers don't consider who's taking care of a patient when they study healthcare. This is a missed opportunity because different doctors can lead
