Researchers have found that people with multiple sclerosis (MS) often show a brain age that’s older than their actual years. This gap, called brain-predicted age difference (brain-PAD), is linked to worse physical disability and trouble with memory or focus. But here’s the big question: Could certai
A new study examined the gene activity in nearly a thousand brain samples from people who had died with Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, Alzheimer’s disease or no brain disease. The researchers used a
Alzheimer’s isn’t just about memory loss—it’s a slow shutdown of the brain’s wiring. For years, scientists have tried to fix this by sending treatments directly to the brain, but the organ’s defenses make it nearly impossible. The tricky part? Most drugs can’t cross the brain’s protective barrier, w
Parkinson’s disease slowly changes how the brain works. It starts when tiny cells that make dopamine begin to disappear. Dopamine is a key messenger in the brain that helps control movement. Without enough of it, people often feel stiff, move slowly, and shake when resting. These problems grow worse
The COVID-19 pandemic has left many people struggling with long-term health issues. One concerning effect is how it might be speeding up memory loss and brain problems, especially for those with Alzheimer's disease. Alzheimer's is a condition that slowly damages the brain, making it hard for people
Alzheimer's disease is a complex puzzle. One key piece? Tiny powerhouses in our cells called mitochondria. These little guys usually help cells stay alive and healthy. But in Alzheimer's, they're not working right. Why? Because calcium, a crucial messenger in cells, is out of balance. Calcium is li
Parkinson's disease (PD) and multiple system atrophy (MSA) are both neurodegenerative disorders that affect the brain and the body's nervous system. The skin, surprisingly, might hold clues about these conditions. Scientists have found evidence that these diseases can also impact the peripheral nerv
Diabetes can cause serious brain problems. These issues can make treating diabetes even harder. So, finding natural compounds that protect the brain could be a game-changer. One such compound is β-sitosterol. It's found in various plants and has shown promise in fighting diabetes-related brain damag
The human brain is a complex organ, and sometimes it goes wrong. One big problem is amyloid aggregation. This is when proteins clump together and become toxic. These toxic clumps can speed up brain diseases. So, scientists are always looking for new ways to stop these clumps from forming. Two speci
PLAN, or PLA2G6-associated neurodegeneration, is a tricky condition. It is a type of neurodegeneration with brain iron accumulation. It can start at any age, from infancy to adulthood. Symptoms can vary widely, affecting movement, thinking, eyesight, and even basic bodily functions. This makes it a
