NFIB

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Jun 26 2025SCIENCE

How Genes Affect Clozapine Levels and Doses

Genes play a big role in how the body handles medicines. One gene, NFIB, has a specific change (rs28379954 T>C) that can affect how much clozapine, a medicine used for treatment-resistant schizophrenia, is in the blood. People with this change need higher doses to feel the medicine's effects. This

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