Imagine a young girl in North India facing a tough battle. She has a rare genetic condition called homozygous familial hypercholesterolemia, or HoFH. This means her body can't process cholesterol properly, leading to very high levels of LDL-C, the "bad" cholesterol. This can cause serious health pro
Skin is the body's biggest shield, constantly fending off environmental dangers and harmful substances. These threats can sometimes lead to skin cancer. Traditional chemotherapy has been a go-to treatment, but its high cost and nasty side effects have left many searching for better options. This
Osteoarthritis (OA) and metabolic syndrome (MetS) are both big problems that get worse as we age. But what's really going on inside our bodies that makes this happen? Scientists dug into public databases to find genes that change with age and might be linked to these conditions. They found 20 genes
Lung cancer is a serious and deadly disease. It comes in different types, with non-small cell lung cancer (NSCLC) being the most common. This type of cancer is tricky to treat, especially in advanced stages. Scientists are now looking closely at genes involved in metabolism, especially those that co
The deaths of Gene Hackman and his wife, Betsy Arakawa, have left investigators with more questions than answers. The couple was found deceased in their Santa Fe home, along with one of their dogs. The other two dogs were found alive and well, but the mystery deepens as investigators consider multip
Kidneys are vital organs that filter waste from our blood. When someone receives a new kidney, doctors need to keep a close eye on it to make sure it's working properly. Traditionally, this involves invasive procedures like biopsies. However, scientists are exploring new, less invasive methods to mo
Imagine trying to make a big decision with lots of moving parts and uncertainty. That's where decision sciences (DSC) comes in. It's all about studying complex systems to help us make smart choices. Over the past 25 years, the way we teach and study DSC has changed a lot. DSC used to focus
Tuberous sclerosis complex (TSC) is a genetic disorder that can cause tumors to grow in the brain. One type of tumor, called subependymal giant cell astrocytoma (SEGA), is particularly concerning. These tumors can block the flow of cerebrospinal fluid, leading to serious issues like hydrocephalus. B
Girls have two X chromosomes, and this can make them more likely to get autoimmune diseases. These are conditions where the body's immune system attacks itself. Scientists are finding out that the X chromosome plays a big role in this. First, let's talk about something called X Chromosome I
Influenza A virus, or IAV, has a sneaky trick up its sleeve. It's a tiny piece of RNA, called USP30-AS1. This RNA is part of our own genetic material, but the virus hijacks it to help itself multiply. The story begins with a pathway in our cells called JAK-STAT. When IAV invades, this pathway kicks
