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People who take semaglutide or tirzepatide often lose a lot of weight while on the drugs. The tricky part is figuring out what happens after they stop taking them. A new analysis looked closely at how quickly the weight tends to come back. Researchers gathered data from six studies covering 1,776 participants. They tracked weight changes for anywhere from 4 to 52 weeks after treatment ended. Using a Bayesian statistical model, they worked out a few key numbers. On average, people had lost about 15. 35 kilograms by the time they stopped the medication. After that, the weight crept back on at roughly 1. 04 kilograms per month. Based on that monthly pace, the model predicted people would regain half of what they had lost within around seven and a half months. A full return to the starting wei

African breadfruit trees grow wild across the continent. For years, these fruits have been pushed aside by imported, carb-heavy foods. Yet they pack serious nutrients and could help build healthier diets. Local growers might finally get a chance to use this underrated resource properly. The researchers decided to look at both seeds and pulp side by side. This was a big shift from past work that only studied seeds. They tried three extraction styles to match traditional practices. Water-based solutions, alcohol blends, and gentle heat were all used. Each method pulled different compounds from the plant material. Surprising patterns emerged from the data. Warming the pulp increased phenolic yields noticeably. Adding alcohol boosted seed extraction even more. Both plant parts showed strong

Wearing headphones all day can make your ears feel hot, sweaty, or itchy. Most people just accept that noise for work or study. But what if you could hear your music or a podcast all by yourself? That way nobody else in the room has to listen. Researchers at Pohang University of Science and Technology built a new speaker called MiPAL. It sends sound with ultrasound so only one person can hear it. The device uses a single tiny speaker instead of many tiny ones. That makes the hardware super simple. The system works by firing ultrasonic waves that turn into audible sound only at a narrow spot. A special front panel acts like a lens, shaping the beam. Behind it, flexible panels stop extra vibrations from leaking out. Unlike other directional speakers that need dozens of emitters, this one u

The hospital and the local paramedic service joined forces to speed up ambulance returns after delivering patients to the emergency department. The collaboration aims to get ambulances back on the road faster while keeping care smooth for patients. Data from this spring shows the unloading time is roughly 44 percent shorter than it was a year earlier, even though the facility is running near full capacity. In spring 2025 the teams introduced a quick check to sort stable patients so they could wait in the waiting room instead of staying on the stretcher. Later they added a system where crews can register patients who can sit upright before a nurse sees them. A special nurse now looks after patients right after they leave the ambulance, letting the main triage nurses focus on those who need

ChatGPT's advertising business reached $1 billion in annualized revenue in about 200 days. That is faster than Google's early ad growth. OpenAI shared this news on Monday. The company also expects $2. 5 billion in ad revenue this year. The ad system started with a pilot in February. It now runs in over 40 countries. Free users and Go plan members see these ads. A self-serve platform launched Monday for marketers in India, Europe, the Middle East, and North Africa. OpenAI says ads are labeled and separate from answers. Advertisers cannot access private chats. The company's total revenue run rate passed $40 billion, roughly double its 2025 end. On the same day, the European Commission called ChatGPT a Very Large Online Search Engine. This is the first time an AI chatbot got this label. It

Researchers looked at Taiwan's Long-Term Care Plan 2. 0 data from 2018 to 2020, linking it with health insurance claims. They wanted to see how different ways older adults use home and community services relate to their medical costs over a year, split by disability level. They used latent class analysis to find groups of service use patterns. Five clear groups came out. Then they used generalized estimating equations to track monthly costs for each group. The group that got both personal help and medical care together tended to have lower or more stable costs, especially for those with moderate or severe disability. In contrast, groups with scattered or separate services showed higher hospital costs. This suggests that mixing personal and medical support might help keep expenses down fo

CNN is rolling out a new weekly email called 20/26 Vision. It starts in early September and runs until the November vote. The focus is the battle for control of the House and Senate. Midterm elections often get less hype than presidential races. Yet they decide which party runs Congress. In 2026 both chambers are up for grabs. Rural voters in Alaska, Latino communities in South Texas, and Mainers watching trade policy could tip the balance. Each Thursday the briefing delivers key polls, major developments, and expert takes. It aims to give readers a clear snapshot without drowning them in data. Links point to deeper coverage for those who want more. President Trump’s second term will be entering its final stretch. His influence on Republican candidates and his trade fights with Canada a

The researchers wanted to see if a short health‑boosting program could help people living with schizophrenia adopt better daily habits. They built a six‑week course that mixed a simple health‑promotion plan with friendly coaching sessions. The goal was to make exercise, nutrition, and stress‑management part of everyday life for participants. Sixty adults were recruited from a local mental health clinic. Half of them were placed in the new program, while the other half continued with standard care. Over six weeks the intervention group attended weekly coaching and practiced the health steps each day. Follow‑up checks happened three months and six months later to see how long the benefits lasted. Those who took part felt noticeably less stressed after the program ended. Their sleep improve

Scientists have built a smart computer system that can spot ankle instability in athletes. The condition, known as chronic ankle instability, shows up when someone keeps twisting their ankle over and over. It mess up the way muscles work, making it hard to stay active. Lots of people deal with this, from weekend warriors to pro sports players. The new system uses tiny sensors you wear on your body. These sensors pick up electrical signals from your muscles. A special computer program then looks at all that information. It groups patients into different types based on how bad their ankle problems are. The program also gives numeric scores that show exactly how well someone can move. Researchers tested this on 150 people. Some had ankle issues, and some did not. The results were impressive

Pregnancy comes with a lot of health risks that can hurt both mom and baby. But getting help fast is tough when doctor visits are short. That's where digital tools might help. A new study looked at what people think about using apps or websites for prenatal care. Researchers talked to 23 moms and 12 healthcare workers in Australia. They wanted to know what kind of info should be in these tools and how they should work. The moms and doctors had clear ideas. They want digital checkups, trusted info tailored to each person, easy-to-use resources, and support that keeps going after the baby is born. They also want tools that send reminders, track health data, and fit into regular doctor visits. Many said early access is key. Having the app before the first appointment helps moms prepare. Th

New research looked at a big question. Can mRNA COVID vaccines help fight cancer when used with immune therapy? Scientists checked Medicare records to find out. They wanted to see if survival rates changed after vaccination. The study used data from over 121,000 patients on cancer drugs. About 10,800 of them took immune checkpoint inhibitors. These drugs help the body spot and attack cancer cells. Researchers noticed something cool. People who got vaccines close to starting treatment lived longer. This happened with mRNA COVID shots. But it also happened with the older type COVID vaccine. And it happened with flu shots too. So what does this mean? The team found no special link between mRNA vaccines and better cancer outcomes. The survival boost showed up no matter which vaccine people g

Glucocorticoids are common drugs in dermatology because they calm inflammation and suppress the immune system. Many earlier experiments have shown that when these hormones enter the body—whether from stress or from taking them by mouth—they can speed up aging in the ovaries. However, it is still unclear whether simply applying a strong steroid cream to the skin can have the same effect. The team used female C57BL/6 mice, six in each group, and applied a very high dose of fluocinolone acetonide to the skin. This supratherapeutic regimen caused the outer and inner layers of the skin to thin and the skin’s protective barrier to weaken. Researchers checked the damage with histology and by measuring barrier markers. After the treatment, the mice’s menstrual‑like cycles stayed regular. Countin

iFAST is a new test that works straight from a positive blood culture. It looks at the electrical changes of many bacteria when antibiotics are added. The result comes in under four hours, no need to wait days. In the first real world study, the test matched the lab method in 97. 8% of cases for Enterobacterales and 97. 2% for non‑fermenting gram‑negative bacteria. Its sensitivity was 96. 8% and 98. 4% respectively, and specificity was 98. 2% and 96. 9%, both above the required 95%. The researchers checked repeatability by testing twelve isolates at three different hospitals, each run three times on separate days with different staff. The agreement stayed around 95. 7%, showing the test is reliable. Doctors need fast answers because delays raise the risk of serious illness. Guidelines say ther

Small farmers in poor countries often skip new methods that would help everyone. These methods boost nutrition, keep food safe, and protect nature. Yet adoption stays low. The reasons are simple. Farmers cannot always see the benefits. Their farms are tiny. The rewards they get do not match the good they do for society. Money and risk play big roles. New seeds or tools cost cash upfront. Loans are hard to get. Information spreads slowly. Farmers weigh what they lose against what they might gain. Often the math does not work for them alone. Policies from different sectors rarely join forces to fix this. Three examples show the pattern. Fighting aflatoxin in crops needs testing and better storage. Biofortified crops add vitamins but yield less at first. Conservation agriculture saves soil

Celtic are scrambling to land a goalkeeper before a tight Tuesday night cutoff. The club must register their Europa League squad with UEFA by 11pm. That deadline comes a full day before the Scottish window shuts. Missing it means any new signing cannot play in the league phase. The urgency stems from Kasper Schmeichel hanging up his gloves this summer. The Bhoys now have a gap between the posts that needs filling fast. Sam Johnstone has emerged as the top target. The 33 year old England international is on the move after Wolves brought in two fresh keepers. Joao Virginia and John Ruddy arrived to push Jose Sa. That pushed Johnstone down the pecking order. Wolves boss Cesar Peixoto said the club had honest talks with him. He confirmed Johnstone will not feature in future plans. The player

In a Massachusetts courtroom, a jury has spent three full days talking things over. They still have not made a decision. The case centers on a former labor and delivery nurse. She stands accused of killing her three children back in 2023. The trial has been closely watched. It shines a bright light on something hard to talk about. That is the mental health of mothers after they give birth. Deliberations kicked off on a Thursday at Plymouth County Superior Court. Before that, jurors sat through a long stretch of testimony. The prosecution called more than 70 witnesses to the stand. One of those witnesses was her husband at the time. The defense brought forward 10 witnesses of its own. All of this unfolded over five weeks of court proceedings. It is a heavy load of evidence for any jury to

A leader stands up to announce AI adoption. The first question cuts through the room. "Is this how layoffs start? " Silence follows. The speaker runs a nonprofit lender and an AI company. They see both sides of the table. Data backs up the fear. Over half of US workers worry about AI at work. Most owners spend months picking tools. Their teams quietly decide whether to trust the project. The team always decides first. The fix works in reverse. Before any software touches a workflow, leaders must name what AI will never touch. Sort every task by judgment, not by function. Three buckets make it simple. Automate means cheap mistakes that fix fast. Assist means the machine drafts and a person approves. Human-owned means the work that earns trust. Nothing in that bucket ever moves. Everyone sho

Lots of people feel alone these days. That feeling is getting stronger in neighborhoods everywhere. A new monthly collection of stories looks at this problem. It shows how some businesses step in when loneliness grows. They offer community, but they also make money from it. One story in the collection looks at surrogacy. Many people think surrogacy is simple. Some call it medical. Others call it a choice. The truth sits somewhere in the middle. Real families face hard questions. They ask what is truly needed and what is optional. Another piece talks about raising kids. Parents want what is best for their children. But they also think about other kids around them. This kind of thinking builds a bigger picture. It shows how choices made at home affect everyone. Then there is a story about

New York counts forty‑one Broadway theaters, each built on valuable real estate. When a production ends, the theater owners begin to wonder which show will take its place. Choosing the right theater isn’t just about having a stage. The size of the house, the stage layout, its location, the budget and the timing all play a role. A show that wants to open in the fall needs a theater that fits its schedule. A limited‑run starring a big name has different needs than a long‑running musical. Putting a production together costs a lot of money and careful planning. Securing a theater is a key piece of that puzzle. Even though the 2025‑26 season earned nearly two billion dollars in ticket sales, some big shows still struggle to break even. So a dark marquee doesn’t mean the lights are out; the c

Finance Minister Purbaya Yudhi Sadewa pointed out several big worries for the world economy. He said fights between countries, especially in the Middle East, could make things shaky. He also warned that countries pulling back from trade and putting up barriers are causing trouble. Another worry he mentioned is the chance of an El Niño event messing with weather and crops. He explained that if the United States and Iran keep clashing, oil prices might jump higher. That could make it harder for factories to get the parts they need and slow down shipping routes. Because of these trade splits, central banks find it tough to decide on interest rates. They have to balance keeping prices steady with helping growth. Global forecasters have cut their expectations for this year. The International