The study followed Chinese adults for 76 weeks. It was a multi‑site, randomized, double‑blind trial. Participants received either a weekly injection of survodutide (3. 6 mg or 4. 8 mg), a placebo, or both plus lifestyle advice. The trial aimed to see if the drug could help people lose weight safely.
To join, people needed a BMI of at least 28, or a BMI of 24 or higher plus another health issue linked to excess weight. The groups were split evenly: one‑third got the lower dose, one‑third got the higher dose, and one‑third got the dummy treatment. Everyone also took part in a lifestyle program.
At the start, 306 volunteers took part. Their average age was about 37. They weighed around 94 kg and had a waist of roughly 106 cm. The average BMI was 33. 2 and triglycerides were 2. 2 mmol/L. Nearly